l carnitine and coq10 capsules L-Carnitine Fumarate - 120 - Pure Encapsulations Nature's Lab Gold CoQ10, Alpha

These include, cabbage, cauliflower, broccoli and mustard greens

This approach operationalizes where, when, how much at the bedside and provides a reproducible scaffold for trials

Electron microscopic analysis of FTD and amyotrophic lateral sclerosis patients with TDP43 pathology revealed prominent mitochondrial impairment, including abnormal and/or depleted cristae, concordant with ultrastructural changes observed in both cellular and animal models of TDP43 proteinopathy (Wang et al., 2019)

This lack of therapeutic success does result in some patients seeking off-label therapies, supplements, and other treatments that lack high-quality levels of evidence but provide hope of altering disease trajectory