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Multiplex quantification of cytokines, hormones and fibrosis markers Concentrations of cytokines, hormones, pro-fibrotic proteins, total protein and collagen were measured in the serum and in BALF samples from patients by multiplex immunoassay analysis (Luminex (R&D) using the Luminex xPONENT software (Thermo Fisher Scientific) and Legendplex (BioLegend)), bicinchoninic acid assay (total protein) or Sircol soluble collagen assay (collagen) according to the manufacturers instructions

Dichloroacetate (DCA) can enhance metformin-induced oxidative damage with simultaneous reduce of metformin promoted lactate production through PDK1 inhibition, suggesting the innovative combinations, such as metformin and DCA, will be promising in expanding breast cancer therapies (302)

'Respiratory muscle dysfunction in animal models of hypoxic disease: Antioxidant therapy goes from strength to strength

doi:10.1016/j.heares.2021.108209