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In addition, we discuss new perspectives with respect to the putative pathophysiological role of cuproptosis in various diseases, as well as the therapeutic potential of targeting this novel form of cell death

95 Gene deletion or the lack of unstable methyl groups in the form of methionine and choline undermines the ability to synthesize SAM, which leads to the development of steatosis and its rapid progress toward NASH

References 1.Singh N., Bhalla M., de Jager P., Gilca M

These concerns necessitate further research, including dedicated long-term safety studies in animal models, specifically designed to assess potential risks associated with higher doses and prolonged exposure