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DPP1 inhibitors: exploring the role of water in the S2 pocket of DPP1 with substituted pyrrolidines
Thus, GSB-106 promoted cell survival with lower potency compared to BDNF, as evident from the half-maximum concentrations of BDNF and GSB-106, which differ by 1 order: EC 50 of 1 nmol for BDNF versus EC 50 10 nmol for GSB-106
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However, more studies are needed to properly observe its effects and recommended dosage
