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Chen JW, Gong RH, Teng C, Lin YS, Shen LS, Lin Z, et al
The implication here is that decreased melatonin production due to the genetic variant may be causally involved in autism.[ref] Related article : ADHD Genes and Root Causes Irritable Bowel Syndrome: There have been several clinical trials using melatonin to help with IBS symptoms

Ganguli M, Dodge HH, Shen C, Pandav RS, DeKosky ST
