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Increased expression and release of PTGS2 in the prostate is associated with ferroptosis, which promotes arachidonic acid metabolism and the release of inflammatory factors through the upregulation of PTGS2 [11]
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Kharaziha M, Baidya A, Annabi N
Furthermore, in some cancers, excess GPx1 may allow for cell survival and promote cell growth by decreasing apoptosis or by stabilizing the activity of oncogenic proteins [142144, 148] (Figure 6)
