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Additionally, hypothalamic ACE2 receptors are implicated in the suppression of corticotropin-releasing hormone synthesis, which is a crucial component of the physiological stress response [96-101]

Generally, L-theanine has strong antioxidant activity, which can be associated with the regulation of the expression and activities of antioxidant-related enzymes

L-carnitine also aids in the removal of harmful chemicals from the body, such as excess acyl-CoA molecules produced during fatty acid metabolism

This was also supported by the downregulated expressions of glycolysis-related genes ( PFK and PK ) in muscle, and the upregulated expressions in gluconeogenesis-related genes ( PECK1 and G6Pa ) in the liver