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Abstract Current lifestyles bring about an increasing prevalence of unhealthy habits that can negatively affect male fertility

In analogy to the MDR phenomenon in cancer cells, Kurelec and collegues adopted the term "multixenobiotic resistance (MXR) proteins" for ABC drug efflux transport in aquatic animals, emphasizing the biochemical protective functions of the cellular pumps against environmental pollution

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Five novel hydrazones were identified as the condensation of isoniazid with keto acids that are intermediates in the metabolism of leucine and/or isoleucine, lysine, tyrosine, tryptophan, and phenylalanine