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Furthermore, although LC-MS lipidomics established the distinct dependence of ferroptosis on PL oxidation, this approach falls short of determining which cells and subcellular compartments are involved in the initiation and subsequent stages of PL peroxidation

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Some patients report changes in sleep, recovery, or energy within weeks, while other changes may take longer depending on the treatment plan and clinical context

Despite caspase-3 activation and the hallmark feature of PS exposure mediated by XKR8, commonly associated with early apoptosis, our findings highlight key distinctions between NETosis and classical apoptosis