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As a result, the k cat / K m of K240A toward both tyrosine and DOPA was also decreased, indicating that mutation of lysine-240 to alanine might affect the affinity of enzyme and substrates by altering the conformation of adjacent amino acids, particularly H241

Depending on an individuals metabolic status and the fatty acid composition in the test meal, these reactions may vary

(96) evaluated the regulation of TSH production in adult male offspring of Wistar rats perinatally exposed to GBH (5 or 50 mg/kg) during the period of hypothalamic sexual differentiation (gestational 18 to postnatal day 5)

10.1074/jbc.274.34.24202
