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Glutathione is often referred to as the master antioxidant due to its powerful detoxifying properties

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Previous studies suggested that GLP-1 diabetes and weight loss drugs, such as semaglutide (brand name Wegovy or Ozempic), could worsen diabetic retinopathy and associated conditions

Third, clinical translation should include establishing multicenter ALS biobanks to validate associations between biomarkers such as ACSL4 and GPX4 and clinical measures including ALSFRS-R scores and survival, and conducting combined trials of ferroptosis inhibitors with mitochondrial protectants to evaluate therapeutic benefit in sporadic ALS