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Description
The final mitochondrial step involves the insertion of ferrous iron into the protoporphyrin ring to form the heme group by ferrochelatase (FECH) 31
Concurrently, by applying controlled doses and durations of OS intervention, we should systematically evaluate changes in phosphorylation levels of key hormone signaling pathways and the transcriptional activity of hormone receptors
In addition, combined treatment with GPNA and a monoclonal antibody (cetuximab) targeting EGFR effectively suppressed the growth of gastric cancer cells in vitro and in vivo 86
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Pharmaceutics 13 , 1042 (2021)
