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Evaluation of the antidepressant-like activity of Convolvulus pluricaulis Choisy in the mouse forced swim and tail suspension tests
The thioredoxin antioxidant system
The comparison shows that concentration selection depends on three primary factors: subject body weight (smaller subjects require smaller volumes), target dose range (higher doses favor higher concentrations to avoid excessive injection volumes), and measurement precision (volumes below 0.05ml approach the reliability limit of standard 1ml insulin syringes even with 0.01ml graduations)
Science Advances 11(8), 2025
