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Description
Axons are injured by antigen-specific CD8 + T cells through a MHC class I-and granzyme B-dependent mechanism

Authors concluded that similar alterations in gene expression may also be present in other cells
Brain 126(12):27612772 Tranchant C, Fleury M, Moreira M, Koenig M, Warter J (2003) Phenotypic variability of aprataxin gene mutations

This should not be construed as a contraindication to the use of AOXs
