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To compare the level of gene transcription in PBMCs after stimulation with 10 g/ml MAP antigen (PPDa) (BOVIGAM Tuberculin PPD Stimulating Antigen, avian), the non-stimulated cells were used as a calibrator and all the upregulation and downregulation of the genes in stimulated cells are compared to the non-stimulated homolog of the same sample

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This targeted mechanism minimizes the risk of off-target effects and supports the compounds favorable safety profile

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