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Kadia T, Ravandi F, Daver N, Borthakur G , Cortes JE, Jabbour E, Kornblau SM, Verstovsek S, Wierda W, Burger JA, Estrov Z, DiNardo C, Dong XQ, Pemmaraju N, Ohanian M, Takahashi K, Hendrickson S, Kantarjian H, Garcia-Manero G

The increase in fatty acid oxidation upon genetic upregulation of Nrf2 is interesting because it accords with an earlier study in which expression of the oxidized-LDL scavenger receptor CD36 in macrophages was reported to be controlled by Nrf2 [133], suggesting that the increase in fatty acid oxidation is coupled with increased uptake of lipids

Bronchial LN (BLN) cells isolated from the Trx-Tg mice produced an equal amount of Th2 cytokines IL-4, IL-5 and IL-13 as the BLN cells of WT mice after leaving the high Trx environment