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Topical numbing creams are usually applied before the procedure to minimize pain

All the geometry structures of reactants (glutaraldehyde, NAD1, ethanethiol, and 4-ethylphenol), intermediates, transition states, and glutarate were optimized with the B3LYP method and 6-31+G(d,p) basis set
The further analysis showed that G/D-CuP could significantly enhance the transition of macrophage phenotypes from M1 to M2 (Fig