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Description
A novel cyano derivative of 11-keto--boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells

doi: 10.4049/JIMMUNOL.181.6.3850 167 NettisEDistasoMSaittaSCasciaroMCristaniMSaijaAet al

This comprehensive approach identifies ideal candidates while protecting at-risk individuals

In the clinical development program, omaveloxolone was generally well tolerated with few discontinuations and serious adverse events (SAEs) and most treatment-emergent adverse events (TEAEs) being mild to moderate in severity [16, 18, 19]
