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Another feature of the recovery process is the removal of damaged mitochondria by a form of autophagy termed mitophagy84,85, and inhibition of mitophagy by lysosomal cholesterol accumulation was shown to sensitize mice to APAP hepatotoxicity86

doi: 10.3389/fped.2014.00066 Received 09 May 2014 Accepted 09 June 2014 Published 27 June 2014 Volume 2 - 2014 Edited by Roberto Canitano, University Hospital of Siena, Italy Reviewed by Andrew Walter Zimmerman, Harvard Medical School, USA

Given the paucity of studies focusing on the distinct function of B cells in PD or other neurodegenerative diseases (103, 105), a more profound understanding of B cell function might reveal new opportunities for disease modification

When methylation functions efficiently, it enables cells to grow, repair, communicate, and respond appropriately to their environment