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Relevance of oxidative pathways in the pathophysiology of chronic kidney disease

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In particular, NQO1 is a detoxificant enzyme that protects cells from oxidative stress by lowering ROS, protecting DNA, proteins and lipids from hyperoxia-mediated damage (Burke et al., 2021)

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Additional details of all procedures are described in the next sections

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The role of GGT in carcinogenesis and particularly the changes in methylation status, changes in GGT mRNA type and GGT isoforms in hepatocarcinogenesis, and the potential role of GGT in chemotherapy-resistant cancers have been reviewed elsewhere [19]

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