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reported five patients with homozygous SDHAF1 mutations, all of whom had motor degeneration and spastic paraplegia, with only one patient experiencing seizures (78)
[DOI] [PubMed] [Google Scholar] Schlicker E., Fink K., Detzner M., Gothert M
Therefore, despite facing multiple obstacles, AI continues to be regarded as a disruptive tool in drug discovery
Indeed, EGR-1 was found to contribute to the pathogenesis of atherosclerosis [123], stenosed calcific valvular disease [124], and cardiac hypertrophy [125,126]
