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The physiological functions of TMAO in the host are determined by these features, such as influencing the protein unfolding or endoplasmic reticulum stress response in cells (51)

The effect of insulin on leucine flux has been investigated in humans with use of an intravenous infusion of insulin combined with [1- 13 C] or [1- 14 C]-leucine tracer [28,29,30]


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