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Our study revealed that GHK-Cu treated 5xFAD mice exhibited improved cognitive performance compared to saline-treated cohorts while also demonstrating a reduction in amyloid plaques in the midbrain, frontal cortex and hippocampus

Downregulation of EAAT2 also contributes to the pathogenesis of neurodegenerative diseases, epilepsy, migraine and depression, as described in the previous sections

Hyperkalemia (elevated potassium) and hypokalemia (low potassium) both disrupt the electrical signals that coordinate heartbeats

In most cases the mutation causes instability of the protein: since mature red blood cells cannot make proteins, the enzyme activity with which a reticulocyte is endowed will decay as the red blood cell ages in circulation