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Even Chew et al., who were able to establish cell lines with samples up to 48 hours post resection, noted that time from surgical resection to laboratory processing is a determining factor in the establishment of new patient-derived cell lines 26

This study received approval from the SingHealth Centralized Institutional Review Board (CIRB Ref: 202008-00040), and all participants provided written informed consent

Epigenetic drugs may assist in this endeavor as they are thought to be capable of sensitizing drug resistant cancer cells to other drugs [73,74,75,107,111,112], and recent studies have supported these propositions [108,110]

4,173 In a meta-analysis that included data from 12 randomized controlled trials with a total of 717 participants, those treated with rTMS had significantly lower Tinnitus Handicap Inventory scores than those who received sham therapy at both one month and six months after treatment