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Moreover, britanin, a bioactive terpenoid extracted from Inula lineariifolia , increased intracellular GPX4 and GSH levels and diminished ferroptosis-induced MIR injury via AMPK/GSK3/Nrf2 signaling [90]

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Expanding its therapeutic horizons, Nuedexta is being investigated for its benefits in ALS, where it may provide neuroprotection by targeting the sigma-1 receptor and limiting glutamate-induced excitotoxicity (50)

[DOI] [PubMed] [Google Scholar] 17.Garcia-Ruiz C, Fernndez-Checa JC