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One idea is to enhance the activity of amino acid metabolism of CAR-T cells by adding cytokines that promote the expression of transporters related to amino acid metabolism, such as SLC1A5, SLC3A2 and SLC7A5, or directly importing transcripts encoding these AATs into T cells

Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity

5 Therapeutic perspectives and challenges Ferroptosis is closely related to orthopaedic diseases, and inhibiting ferroptosis in patients with related orthopaedic diseases may constitute a new treatment method

Risk of iron overload in obesity and implications in metabolic health