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By sequestering actin monomers and controlling their polymerization into filaments, TB-500 enables enhanced migration of fibroblasts, endothelial cells, and immune cells to injury sites

Thus, it was concluded that a combination treatment is highly efficacious and tolerable in treating vitiligo

The molecule incorporates a C20 fatty diacid moiety linked via a gamma-glutamic acid spacer, which binds to serum albumin and confers the extended 5-day half-life enabling once-weekly dosing
