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In addition, CSF and serum analyses indicated increased levels of dopamine, TGF-1, IL-4 and IL-10, and a decrease in TNF- and IL-1 [71]
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The authors stratified their results based on the severity of hepatic encephalopathy at the time of inclusion and demonstrated that NAC-treated patients with mild hepatic encephalopathy (grade I and II) had better survival compared to controls
35), suggesting a higher bioavailability of NP4 in comparison to Ru(II)-OH
