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Description
Purity: 99% by HPLC
Methods The PubMed, Cochrane Library, Embase, and Web of Science databases were searched up to the April 1, 2024
Here, working primarily in mouse hepatocytes, we show that decreasing the availability of substrate for the TCA cycle diminished NADPH production and attenuated ER stress in a manner that depended on glutathione oxidation
Given that high SLC7A11 expression is a key feature of certain cancers, these findings indicate that disulfidptosis could serve as the basis of innovative anti-cancer therapies
