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3 Biotech 13 , 311 (2023)

Oncotarget 2020 Nov 3;11(44):3921-3932

The morphine metabolite morphinone reacts with glutathione to form a covalent adduct that is then excreted in urine
Unlike dopaminergic or GABAergic compounds that cause receptor downregulation, c-Met receptor density doesn't decrease with prolonged agonist exposure in published models
