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Introduction and history of the chemistry of nucleic acids therapeutics

As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)

Cerebral amyloid-beta PET with florbetaben (18F) in patients with Alzheimers disease and healthy controls: A multicentre phase 2 diagnostic study

Not surprisingly, patients are increasingly seeking information on the role of diet in the treatment and prevention of thyroid diseases in daily clinical practice