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It is not FDA-approved for human therapeutic use, and most evidence involves preclinical studies, animal models, and limited early human safety data

J.FarhavarA.GeeC.HawthornB.HeH.NayakA.et al (2009)

BAFF stimulates aberrant B-cell maturation, leading to the emergence of self-reactive B cells, which locally produce autoantibodies, in a germinal centre-like structure (GC-like), which is also the location of lymphomagenesis (origin of lymphoma)

the frequency and dosage will vary also according to factors specific for each patient depending on the specific therapies (e.g., the specific therapeutic or prophylactic agent or agents) administered, the severity of the disorder, disease, or condition, the route of administration, as well as age, body, weight, response, and the past medical history of the patient