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Considering the current evidence for an interference of vitamin E with the metabolism of vitamin K, the finding that high-dose vitamin E intake suppresses vitamin K status and may consequently have negative impact on physiological processes requires further verification and investigation

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However, it is hypothesized that DSIP may target several specific receptors, which are considered crucial in its function

VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: Implications for giant cell tumour pathobiology