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Opicinumab, an anti-LINGO1 monoclonal antibody that modulates OPC differentiation to enhance remyelination, was tested in pilot phase II studies in optic neuritis and relapsing-remitting multiple sclerosis (RRMS) (RENEW and SYNERGY trials) 87,88

ZhangHCaoXYWangLNTongQSunHMGanCTet al

That said, sermorelin also supports improved body composition over time it just works more gradually

bidirectional modulation of innate and adaptive immune responses (Si et al., 2025)
