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Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

They work through different mechanisms and serve different purposes

Seborrheic Keratosis Asymmetric pigmented follicular openings (pseudonetwork) Progression of findings: Early stage: peppering of pigmentation around follicular ostia ( blue-gray dots ) Coalescence of blue-gray dots into polygonal lines and rhomboidal structures Late stage: homogeneous Homogeneous Imaging of the Spleen dark-brown to black blotches blocking the follicular ostia Reflectance confocal microscopy Availability of this technique is limited

We propose a more consistent format for representing lipid structures where, in the simplest case of the fatty acyl derivatives, the acid group (or equivalent) is drawn on the right and the hydrophobic hydrocarbon chain is on the left (see Fig