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This NAD+ elevation activates sirtuins (particularly SIRT1), enhances mitochondrial function, and preserves methylation capacity by reducing S-adenosylmethionine (SAM) consumption
The lack of protection and repair capabilities can leave nerves vulnerable to damage
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The NHS symptoms list includes persistent tiredness, tingling or numbness in the hands and feet, mouth ulcers, a sore red tongue and problems with memory or concentration
