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Study limitations Although the current findings are consistent and coherent, strongly indicating the external validity of the study, we do recommend future preferably large prospective clinical trials, to increase their internal validity

Anti-MuRF1 (1:1000, GTX110475) was purchased from GeneTex (Irvine, CA, USA)

13 Another study found that patients with MDD had significantly lower plasma levels of ALC compared to healthy controls, and these levels were inversely correlated with depression severity and duration

Methionine is a precursor used by the body in the manufacture of taurine