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10.1093/eurheartj/ehx393 88 ImamM
Compounds such as melatonin, N-acetylcysteine, vitamin C, and selenium have demonstrated protective effects in preclinical and some clinical studies by enhancing mitochondrial integrity and reducing systemic inflammation (Mantzarlis et al., 2017
The synthesis of CRP is mainly controlled by IL-6 but IL-1 and TNF- may influence CRP levels as well and increase of CRP in blood and other body fluids is a constant result of these proinlammatory cytokines [15,16]
[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Borchardt T, Helmke A, Ernst J, Emmert S, Schilling AF, Felmerer G, et al
