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This paper reports a method for quantifying metabolic fluxes in tumours in mice and concludes that TCA cycle flux is low in primary tumours owing to low demand for ATP, but is higher in metastatic tumours
15 They explain that vitamin C is a cofactor for the enzyme peptidylglycine -amidating monooxygenase (PAM), 137 the only known enzyme in humans capable of making essential modifications to peptide hormone precursors
10.1002/ptr.7176 71 MansourS
J., Fijnvandraat K
