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A single instance of leaving your vial at room temperature overnight can denature the protein structure irreversiblyturning an expensive research compound into sterile water with no visual indication that anything changed
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doi: 10.1007/s00109-011-0845-0
In the resting state, continuous IGF1 stimulation ultimately induced down-regulation of Akt or ERK and Foxo3a activation, thereby inhibiting proliferation and enhancing self-renewal
