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Description
Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines

In particular, the improvement of intestinal wall integrity occurs due to the three main mechanisms: i) increased expression of TJ proteins, ii) decreased levels of pro-inflammatory molecules, and iii) increased intracellular antioxidant potential (Sandoval-Ramrez et al., 2021)

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FOXO4-DRI was designed to compete with endogenous FOXO4 for p53 binding, releasing p53 to activate apoptotic pathways selectively in senescent cells