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Jonckheeres trend test revealed a positive dose response (p less than 0.05) for the following adverse events: fatigue, impotence, insomnia, sweating increased, somnolence, and yawning

doi: 10.1080/1745039X.2017.1421340 28 TamaiIOhashiRNezuJYabuuchiHOkuAShimaneMet al

Dietary polyphenols such as naringenin have been shown to restore microbial balance, suppress pathogenic bacteria, and promote beneficial strains, ultimately reinforcing intestinal barrier integrity

doi: 10.1038/nm.3145 35 KristofferB.SkoogI.GustafsonD
