glutathione plasma uptake Metabolism of system and the interaction with ROS and RNS Protein S-glutathionylation confers cellular resistance

Originally derived from a body protection compound (BPC) found in the stomach, this synthetic peptide is known for its regenerative properties and potential benefits in wound healing, muscle recovery, and digestive health

If SCoV2 is targeting GSH biosynthesis as well as TXNRD1 and GPx1 for proteolytic knockdown, in infected cells, the resulting decreases in these critical antioxidant molecules would contribute to increased oxidative stress, NF-B activation and pro-apoptotic signaling ( these consequences of virus-mediated proteolysis would be taking place in everyone who is actively infected, regardless of their Se status , and would thus be consistent with results suggesting that Se intakes up to several times the minimal dietary requirement are associated with an increase in cure rate from COVID-19 (Figure 2) and the stochastic nature of such molecular interactions

Who May Be a Candidate for Peptide Therapy

Shinde S, Lee LH, Chu T