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They revealed that activation of the MAPK pathway by ROS generated during ferroptosis could activate the transcription factor TFEB, which in turn induced the expression of genes involved in lysosomal biogenesis and autophagy
Journal of Biological Chemistry , 267 ( 34 ), 2483324840
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In addition, TD is difficult to diagnose because there are no cheap and reliable laboratory tests to detect the deficiency-serum thiamine levels are not adequate to determine the body's supply of thiamine
