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However, in the LPS-induced ALI animal models, honokiol could activate the sirtuin 3 (SIRT3)/AMP-activated protein kinase (AMPK) axis and inhibit the expression of Ang- to protect the pulmonary microvascular endothelial barrier (Lan et al., 2018)

Our team strongly advises against it due to the unpredictable nature of such interactions

Kerem Z, Bilkis I, Flaishman MA, Sivan L (2006) Antioxidant activity and inhibition of alpha-glucosidase by trans-resveratrol, piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L

Ferroptosis was recently implicated as a mechanism of neurodegeneration in Alzheimers Disease [71], and as a mechanism for neuroinflammation in Parkinsons Disease [85,86]