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In a similar experimental model, HD significantly decreased hepatic TGF1, hydroxyproline, the serum liver function markers of ALT, AST and total bilirubin, the hepatic content of MDA and myeloperoxidase activity, the serum pro-inflammatory cytokine TNF-, relative liver weight, and the serum lipid profile markers cholesterol, triglycerides and low-density lipoprotein compared with the reference drug SL, which suggested that HD may be a promising protective agent against liver fibrosis (Nasehi et al., 2023)

The flow cytometry data collected from 0 to 72 h in terms of FSC (linearly related to cell size) (Fig 1B) and SSC (cellular granularity) (Fig 1C) also correlate with an alternative measurement, i.e., the Coulter volume measurements (Fig 1D), and showed that whereas 5 M NaAsO 2 induced cell shrinkage associated with increased granularity, As 2 O 3 provoked cellular swelling with quite fixed granularity

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