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Description
VPA protein binding becomes saturated with overdose meaning there may be more free valproate accessible to removal from the circulation
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however, it is advisable to seek advice from a professional
Additionally, girls with Rett syndrome will often have extrapyramidal disturbances, including bruxism (97%), excessive drooling (75%) oculogyric crises (63%), hypomimia (63%), dystonia (59%), rigidity (44%), bradykinesia (41%), and proximal myoclonus (34%) (81)
