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Reactive astrogliosis in neuroinfection is thus defensive and neuroprotective: inhibition of astrocytic reactivity, for example by knocking out GFAP, 231 or by genetic deletion of NK-1R receptor for substance P, which suppresses reactive astrogliosis that defines resistance to N

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Measurements were performed using an in-house developed and validated (ISO9001 certified) multiplex immunoassay based on Luminex xMAP technology (Luminex, Austin TX USA) as described ( Flow Cytometry Cells (1 x 10 5 ) were seeded in 12-well plates