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Manage., 2018, 206, 749762 CrossRef CAS

NPs, a distinct subclass of MPs, possess smaller dimensions, a larger surface-to-volume ratio, and greater chemical reactivity than MPs, enhancing their capacity to disrupt metabolism and impair reproduction in animals 15,16

For the participants who finished phase 2, there was little change in severity of diarrhea (0.52 +/-0.79 at beginning, 0.57 +/- 0.79 at end) and a small increase in severity of constipation (0.61 +/- 0.89 to 0.87 +/- 1.1, not significant)
