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It includes a wide range of bioactive compounds that are released by the oocyte itself, as well as by the granulosa, cumulus, and theca cells that surround it

[DOI] [PubMed] [Google Scholar] 85.Pollack A

Because of that, RA treatment should remain primarily based on DMARDs (conventional or biological), with antioxidants considered as potential concomitant therapy in certain and selected patients

If you experience purging the first time you use retinol or a leave-on exfoliant, it can be tempting to stop using the product immediately
